oxidized glutathione - significado y definición. Qué es oxidized glutathione
DICLIB.COM
Herramientas lingüísticas IA
Ingrese una palabra o frase en cualquier idioma 👆
Idioma:     

Traducción y análisis de palabras por inteligencia artificial

En esta página puede obtener un análisis detallado de una palabra o frase, producido utilizando la mejor tecnología de inteligencia artificial hasta la fecha:

  • cómo se usa la palabra
  • frecuencia de uso
  • se utiliza con más frecuencia en el habla oral o escrita
  • opciones de traducción
  • ejemplos de uso (varias frases con traducción)
  • etimología

Qué (quién) es oxidized glutathione - definición

CHEMICAL COMPOUND
Glutathione disulphide; GSSG; Oxidized glutathione; Oxiglutatione

Glutathione—CoA-glutathione transhydrogenase         
CLASS OF ENZYMES
Glutathione--CoA-glutathione transhydrogenase; Glutathione-CoA-glutathione transhydrogenase; EC 1.8.4.3; CoA:glutathione-disulfide oxidoreductase
In enzymology, a glutathione—CoA-glutathione transhydrogenase () is an enzyme that catalyzes the chemical reaction
S-(hydroxymethyl)glutathione synthase         
INTERPRO FAMILY
EC 4.4.1.22; S-(hydroxymethyl)glutathione formaldehyde-lyase (glutathione-forming)
In enzymology, a S-(hydroxymethyl)glutathione synthase () is an enzyme that catalyzes the chemical reaction
Glutathione synthetase deficiency         
HUMAN DISEASE
Deficiency of glutathione synthase; Deficiency of glutathione synthetase; 5-oxoprolinemia; 5-oxoprolinuria; Pyroglutamic acidemia; Pyroglutamic aciduria
Glutathione synthetase deficiency (GSD) is a rare autosomal recessive metabolic disorder that prevents the production of glutathione. Glutathione helps prevent damage to cells by neutralizing harmful molecules generated during energy production.

Wikipedia

Glutathione disulfide

Glutathione disulfide (GSSG) is a disulfide derived from two glutathione molecules.

In living cells, glutathione disulfide is reduced into two molecules of glutathione with reducing equivalents from the coenzyme NADPH. This reaction is catalyzed by the enzyme glutathione reductase.

Antioxidant enzymes, such as glutathione peroxidases and peroxiredoxins, generate glutathione disulfide during the reduction of peroxides such as hydrogen peroxide (H2O2) and organic hydroperoxides (ROOH):

2 GSH + ROOH → GSSG + ROH + H2O

Other enzymes, such as glutaredoxins, generate glutathione disulfide through thiol-disulfide exchange with protein disulfide bonds or other low molecular mass compounds, such as coenzyme A disulfide or dehydroascorbic acid.

2 GSH + R-S-S-R → GSSG + 2 RSH

The GSH:GSSG ratio is therefore an important bioindicator of cellular health, with a higher ratio signifying less oxidative stress in the organism. A lower ratio may even be indicative of neurodegenerative diseases, such as Parkinson's disease (PD) and Alzheimer's disease.